NIBRA-CS®
NIBRA-CS® (Non-Invasive Baro-Reflex Assessment – Combined System) is a patented, CDSCO-licensed point-of-care autonomic neurofunction assessment platform developed by Inovocare Healthsoft Solutions Pvt. Ltd.
Designed as a portable, standalone diagnostic solution, NIBRA-CS® integrates structured autonomic assessment, physiological signal acquisition, HRV analysis and digital reporting within a single system, with minimal infrastructural requirements.
Early Assessment of Autonomic Dysfunction
Autonomic dysfunction can be associated with diabetes, ageing, long COVID, cardiovascular disorders and other chronic health conditions. It may develop gradually and remain undetected until complications become apparent.
- Gradual & Often Under-Recognised
- Multiple Assessment Components
- Infrastructure & Workflow
- Access Beyond Specialised Settings
About NIBRA-CS®
NIBRA-CS® (Non-Invasive Baro-Reflex Assessment – Combined System) is an indigenous, patented medical device developed by Inovocare Healthsoft Solutions Pvt. Ltd., India, for autonomic neurofunction assessment.
The system integrates structured cardiovascular autonomic reflex testing with electrocardiographic and physiological signal acquisition, Heart Rate Variability (HRV) analysis and digital reporting within a portable, standalone system.
NIBRA-CS® supports structured autonomic assessment through physiological manoeuvres including deep breathing, standing response, Valsalva manoeuvre and sustained handgrip, together with cardiovascular response assessment and HRV analysis.
Designed for point-of-care and lower-resource clinical environments, NIBRA-CS® represents an indigenous medical-device innovation focused on the integration, portability and deployment of established autonomic assessment methods within a single workflow.
| Parameter | Details |
|---|---|
| Product Name | NIBRA-CS® |
| Product Category | Autonomic Neurofunction Assessment Device |
| Technology Type | Standalone Medical Device with Digital Analysis |
| Primary Focus | Cardiovascular Autonomic Function Assessment |
| Target Users | Hospitals, Clinics, Medical Colleges & Clinical Researchers |
| Patent Status | Indian Patent Granted |
| Regulatory Status | CDSCO MD-5 Licensed |
| Commercial Status | Commercial Status — Verify with Manufacturer |
| Innovation Support | BIRAC BIG • NIDHI Prayas • AGC JanCare |
Patient Preparation
The patient is prepared for the selected autonomic assessment and the required physiological measurements are initiated.
Physiological Signal Acquisition
ECG and other required physiological signals are acquired through the NIBRA-CS® system during the assessment.
Structured Autonomic Testing
Appropriate autonomic manoeuvres, including deep breathing, standing, Valsalva manoeuvre and sustained handgrip, are performed according to the assessment protocol
Cardiovascular Response Assessment
Cardiovascular responses associated with the selected autonomic tests are captured and assessed, including relevant heart-rate and blood-pressure responses.
Autonomic & HRV Analysis
The acquired physiological data are analysed to assess autonomic responses and Heart Rate Variability, including short-term, time-domain and frequency-domain parameters.
Digital Report
The assessment findings are compiled into an integrated digital report to support interpretation by qualified healthcare professionals.
Autonomic Assessment
- Cardiovascular autonomic reflex assessment
- Parasympathetic function assessment
- Sympathetic function assessment
- Structured autonomic manoeuvres
- Heart Rate Variability (HRV) assessment
Integrated Physiological Assessment
- ECG and physiological signal acquisition
- Cardiovascular response assessment
- Deep breathing assessment
- Standing response assessment
- Valsalva manoeuvre assessment
- Sustained handgrip assessment
Analysis & Digital Reporting
- Short-term HRV analysis
- Time-domain HRV analysis
- Frequency-domain HRV analysis
- Integrated digital analysis
- Structured digital reporting
Portable & Standalone Design
- Standalone system architecture
- Portable design
- Point-of-care orientation
- Digital-health enabled
- Designed for lower-resource clinical environments
For Healthcare Professionals
- Structured autonomic assessment workflow
- Integrated cardiovascular autonomic and HRV assessment
- ECG and physiological signal acquisition
- Digital analysis and reporting
- Portable, standalone system
For Hospitals & Institutions
- Portable assessment system
- Point-of-care deployment potential
- Standalone operation
- Designed for lower-resource clinical environments
- Supports clinical, institutional and research applications
For Patients
- Non-invasive assessment approach
- Potential for assessment closer to the point of care
- Structured evaluation of cardiovascular autonomic responses
- Digital assessment workflow
For Healthcare Systems
- Portable autonomic assessment technology
- Point-of-care deployment orientation
- Potential use across varied clinical environments
- Digital-health enabled workflow
- Supports broader access to structured autonomic assessment
- Diabetes Care
- Endocrine & Metabolic Care
- Neurological Assessment
- Geriatric Care
- Post-COVID / Long COVID Assessment
- Cardiovascular Risk Assessment
- Clinical Screening
- Clinical Research
Healthcare Professionals
- Physicians
- Diabetologists
- Neurologists
- Geriatric Care Professionals
- Other qualified healthcare professionals involved in autonomic assessment
Healthcare & Academic Institutions
- Hospitals
- Medical Colleges
- Clinical Departments
- Academic Healthcare Institutions
- Clinical Research Institutions
Research & Clinical Programs
- Clinical Research Teams
- Medical Researchers
- Autonomic Function Research
- Institutional Clinical Studies
- Screening & Assessment Programs
NIBRA-CS® has progressed through product development, clinical and institutional testing, and deployment across healthcare and academic settings.
According to information provided by the manufacturer, 500+ patients have been tested during the product's development and clinical journey.
The manufacturer has also reported institutional engagements involving hospitals and academic/medical institutions, supporting the continued development and use of NIBRA-CS® for autonomic neurofunction assessment.
NIBRA-CS® has progressed through an Indian medical-device development journey involving innovation support, intellectual-property protection, clinical and institutional testing, regulatory progression and public launch.
The milestones below reflect recognition, development support and reported product-development achievements associated with NIBRA-CS® as provided by the manufacturer.
- BIRAC BIG Support
- NIDHI PRAYAS Support
- AGC JanCare Recognition
- Global Bio India Launch
- Indigenous Medical-Device Development
- Standalone system architecture Designed to operate as a standalone system rather than depending on a conventional separate PC-based testing setup.
- Portable assessment system Designed for portability, supporting deployment across appropriate clinical and institutional environments.
- Point-of-care deployment orientation Designed to bring integrated autonomic assessment closer to appropriate clinical and lower-resource care environments.
- Integrated autonomic assessment Combines structured cardiovascular autonomic reflex testing, physiological signal acquisition, HRV analysis and digital reporting within a single system.
- Integrated digital analysis and reporting Brings physiological data acquisition, HRV analysis and digital reporting together within the assessment workflow.
- Indigenous Indian development Developed in India by Inovocare Healthsoft Solutions Pvt. Ltd. as an indigenous medical-device technology.
| Parameter | Status |
|---|---|
| Commercial Availability | To Be Confirmed with Manufacturer |
| Patent Status | Indian Patent Granted |
| CDSCO Licence | MD-5 Licensed |
| Clinical Testing | 500+ Patients Tested* |
| Innovation Support | BIRAC BIG • NIDHI Prayas • AGC JanCare |
| Public Launch | Global Bio-India, New Delhi |
| Institutional Deployment | Reported across clinical & institutional settings |
Inovocare Healthsoft Solutions Pvt. Ltd.
Inovocare Healthsoft Solutions Pvt. Ltd. is the Indian developer and manufacturer associated with NIBRA-CS® (Non-Invasive Baro-Reflex Assessment – Combined System).
The company has developed NIBRA-CS® as an indigenous medical-device technology for autonomic neurofunction assessment, bringing together structured cardiovascular autonomic reflex testing, physiological signal acquisition, HRV analysis and digital reporting within a portable, standalone system.
The company has developed NIBRA-CS® as an indigenous medical-device technology for autonomic neurofunction assessment, bringing together structured cardiovascular autonomic reflex testing, physiological signal acquisition, HRV analysis and digital reporting within a portable, standalone system.
Interested in NIBRA-CS®? Connect with Inovocare through MIIMD for product information, clinical and institutional enquiries, research collaboration, technology partnerships or other opportunities related to the product.
Submit your requirement and the relevant enquiry will be directed towards the appropriate manufacturer engagement channel.
NIBRA-CS® enters an established autonomic-assessment technology category rather than creating the underlying science of autonomic testing. Its significance from an Indian medical-device perspective lies in how established cardiovascular autonomic assessment methods have been integrated into a portable, standalone and digitally enabled system designed for point-of-care and lower-resource clinical environments.
The product brings together structured autonomic reflex testing, physiological signal acquisition, HRV analysis and digital reporting within a single workflow. This makes NIBRA-CS® an interesting example of indigenous medical-device innovation focused not only on technology, but also on how established clinical methods can be engineered for different deployment environments.
MIIMD views NIBRA-CS® as a meaningful example of India's evolving medical-device ecosystem: not because the underlying autonomic tests are newly invented, but because the product represents an Indian effort to integrate, package and deploy those established methods through a newer standalone and point-of-care-oriented architecture. Its longer-term impact will depend on continued clinical evidence, real-world adoption, technical validation and scalability.
